Valacyclovir (Valtrex, marketed by GlaxoSmithKline)and acyclovir (Zovirax, marketed by Sanofi-Aventis) are used mainly for treatment of genital herpes.Both are antiviral drugs and can be taken orally to shorten herpes symptoms or to prevent this infection from recurring in healthy individuals.Acyclovir pills had been in use from 1991 and enjoying the status of a first-of-its-kind antiviral drug for genital herpes treatment,until Valtrex was approved by the US Food and Drug Administration (FDA)4 years later in 1995.The valacyclovir vs acyclovir debate started since then and it still remains a matter of researchinterest as to which drug you can use to cope with herpes better. https://www.lq3pharma.com/valtrex-generic-valacyclovir/has some nice tips on this.
Valacyclovir has a number of key advantages over other similar antiviral medications. Clinical trials have shown that this drug has greater effectiveness in dealing with the herpes simplex virus (HSV) or the varicella zoster virus (VZV), compared to acyclovir or other drugs. Another plus factor of Valtrex is that it is probably the only medicine that can reduce the risk of herpes transmission, given that safe sex methods are used. As far as shingles (herpes zoster) treatment is concerned, valacyclovir can lessen the severity of post-zoster pain quicker than acyclovir.
The GlaxoSmithKline drug also provides better oral bioavailability than acyclovir. It implies that when you take a pill, your circulatory system will receive most of its ingredients unchanged. It is estimated that valacyclovir provides about 70% bioavailability. The risk of drug interactions is also minimum with valacyclovir, compared to some of the other antiviral herpes medicines.
Convenient dosing schedule is one of the major advantages of Valtrex. You can take 500mg Valtrex pills twice a day to reduce the severity of a herpes outbreak. It makes valacyclovir a more convenient option than acyclovir as you need to take the latter drug 5 times a day to get the same kind of results.